Title : Angiotensin II stimulates superoxide production by nitric oxide synthase in thick ascending limbs.

Pub. Date : 2016 Feb

PMID : 26884476






2 Functional Relationships(s)
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1 In the presence of the NOS inhibitor L-NAME, Ang II-stimulated O2 (-) decreased from 2.02 +- 0.29 to 1.10 +- 0.11 RLU/s/mug protein (P < 0.01; n = 8). NG-Nitroarginine Methyl Ester angiotensinogen Rattus norvegicus
2 In the presence of Ang II plus apocynin, a NADPH oxidase inhibitor, L-NAME did not change O2 (-) (0.59 +- 0.04 vs. 0.61 +- x0.08 RLU/s/mug protein; n = 5). NG-Nitroarginine Methyl Ester angiotensinogen Rattus norvegicus