Title : Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3.

Pub. Date : 2016 Mar 22

PMID : 26883108






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Over time cells treated with GSK2830371 accumulated in G1 and G2 phases of the cell cycle in a p21-dependent manner and were prone to induction of senescence by a low dose of MDM2 antagonist nutlin-3. GSK2830371 MDM2 proto-oncogene Homo sapiens