Title : 2-Methoxyestradiol prevents monocyte adhesion to vascular endothelial cells via downregulation of VCAM-1 expression.

Pub. Date : 2016 Jul

PMID : 26880304






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Meanwhile, the nuclear factor kappaB (NF-kappaB) p65 subunit activity and its nuclear translocation was inhibited by 2-ME in HUVECs. 2-Methoxyestradiol RELA proto-oncogene, NF-kB subunit Homo sapiens
2 The PI3K inhibitor wortmannin or the specific Akt siRNA both inhibited the effects of 2-ME, suggesting that 2-ME inhibited p65 activity via PI3K/Akt signaling. 2-Methoxyestradiol RELA proto-oncogene, NF-kB subunit Homo sapiens
3 The PI3K inhibitor wortmannin or the specific Akt siRNA both inhibited the effects of 2-ME, suggesting that 2-ME inhibited p65 activity via PI3K/Akt signaling. 2-Methoxyestradiol RELA proto-oncogene, NF-kB subunit Homo sapiens