Title : Iron mitigates DMT1-mediated manganese cytotoxicity via the ASK1-JNK signaling axis: Implications of iron supplementation for manganese toxicity.

Pub. Date : 2016 Feb 16

PMID : 26878799






1 Functional Relationships(s)
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1 Similarly, direct Fe(2+) chelation also resulted in aggravated Mn(2+)-mediated JNK phosphorylation, while Fe(2+) repletion protected cells, and this occurs via the ASK1-thioredoxin pathway. ammonium ferrous sulfate mitogen-activated protein kinase 8 Homo sapiens