Title : Tributyltin chloride increases phenylephrine-induced contraction and vascular stiffness in mesenteric resistance arteries from female rats.

Pub. Date : 2016 Mar 15

PMID : 26873547






2 Functional Relationships(s)
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1 Moreover, increased superoxide anion production was observed in the mesenteric resistance arteries of TBT rats accompanied by an increase in gp91phox, catalase, AT1 receptor and total ERK1/2 protein expression. Superoxides mitogen activated protein kinase 3 Rattus norvegicus
2 In conclusion, these findings show that TBT induced alterations are most likely due to a reduction of NO production combined with increased O2(-) production derived from NADPH oxidase and ERK1/2 activation. Superoxides mitogen activated protein kinase 3 Rattus norvegicus