Title : RhoA/Rho-kinase activation promotes lung fibrosis in an animal model of systemic sclerosis.

Pub. Date : 2016

PMID : 26873329






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Inhibition of ROCK reduced skin fibrosis, expression of alpha-smooth-muscle actin and 3-nitrotyrosine, as well as the activity of ROCK in the fibrotic skin of HOCl-treated mice, through inhibition of phosphorylation of Smad2/3 and ERK1/2. Hypochlorous Acid SMAD family member 2 Mus musculus