Pub. Date : 2016
PMID : 26863525
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Syncytiotrophoblast hCG secretion is modulated by the partial pressure of oxygen (pO2), reactive oxygen species (ROS) and potassium (K+) channels. | PO-2 | chorionic gonadotropin subunit beta 5 | Homo sapiens |
| 2 | Here we test the hypothesis that K+ channels mediate the effects of pO2 and ROS on hCG secretion. | PO-2 | chorionic gonadotropin subunit beta 5 | Homo sapiens |
| 3 | hCG secretion and 86Rb efflux were significantly greater in explants maintained in 21% pO2 than normoxia. | PO-2 | chorionic gonadotropin subunit beta 5 | Homo sapiens |
| 4 | 4-AP/TEA inhibited hCG secretion to a greater extent at 21% than 6% and 1% pO2, and reduced 86Rb efflux at 21% but not 6% pO2. | PO-2 | chorionic gonadotropin subunit beta 5 | Homo sapiens |
| 5 | LDH release and tissue LDH/hCG were similar in 6%, 21% and 1% pO2 and unaffected by 4-AP/TEA. | PO-2 | chorionic gonadotropin subunit beta 5 | Homo sapiens |
| 6 | ROS effects on both hCG secretion and 86Rb efflux are pO2-dependent but causal links between the two remain to be established. | PO-2 | chorionic gonadotropin subunit beta 5 | Homo sapiens |