Title : On the regulatory importance of 27-hydroxycholesterol in mouse liver.

Pub. Date : 2017 May

PMID : 26851362






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In a previous work triple-knockout mice deficient in the biosynthesis of 24S-hydroxycholesterol, 25-hydroxycholesterol and 27OH were shown to have impaired response to dietary cholesterol, suggesting side-chain oxidized oxysterols to be mediators in cholesterol-induced effects on LXR target genes at a transcriptional level (Chen W. et al., Cell Metab. 25-hydroxycholesterol nuclear receptor subfamily 1, group H, member 3 Mus musculus