Pub. Date : 2016 May
PMID : 26803847
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine treatment led to dose-dependent increases in the phosphorylation of PERK[Thr981] and eIF2alpha[Ser51], whereas pretreatment with a nicotinic acetylcholine receptor (nAChR) antagonist (mecamylamine hydrochloride) blocked the induction of PERK phosphorylation, verifying the direct involvement of nicotine and nAChR binding. | Nicotine | cholinergic receptor nicotinic alpha 2 subunit | Rattus norvegicus |
| 2 | Nicotine treatment led to dose-dependent increases in the phosphorylation of PERK[Thr981] and eIF2alpha[Ser51], whereas pretreatment with a nicotinic acetylcholine receptor (nAChR) antagonist (mecamylamine hydrochloride) blocked the induction of PERK phosphorylation, verifying the direct involvement of nicotine and nAChR binding. | Nicotine | cholinergic receptor nicotinic alpha 2 subunit | Rattus norvegicus |
| 3 | Nicotine treatment led to dose-dependent increases in the phosphorylation of PERK[Thr981] and eIF2alpha[Ser51], whereas pretreatment with a nicotinic acetylcholine receptor (nAChR) antagonist (mecamylamine hydrochloride) blocked the induction of PERK phosphorylation, verifying the direct involvement of nicotine and nAChR binding. | Nicotine | cholinergic receptor nicotinic alpha 2 subunit | Rattus norvegicus |
| 4 | Nicotine treatment led to dose-dependent increases in the phosphorylation of PERK[Thr981] and eIF2alpha[Ser51], whereas pretreatment with a nicotinic acetylcholine receptor (nAChR) antagonist (mecamylamine hydrochloride) blocked the induction of PERK phosphorylation, verifying the direct involvement of nicotine and nAChR binding. | Nicotine | cholinergic receptor nicotinic alpha 2 subunit | Rattus norvegicus |