Pub. Date : 2015 Dec
PMID : 26788167
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Upregulation of the MCL-1S protein variant following dihydroartemisinin treatment induces apoptosis in cholangiocarcinoma cells. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 2 | The aim of the present study was to determine whether dihydroartemisinin (DHA) induces apoptosis in the human cholangiocarcinoma QBC939 cell line through the regulation of myeloid cell leukemia-1 (MCL-1) expression. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 3 | The aim of the present study was to determine whether dihydroartemisinin (DHA) induces apoptosis in the human cholangiocarcinoma QBC939 cell line through the regulation of myeloid cell leukemia-1 (MCL-1) expression. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 4 | The rate of apoptosis and cell cycle changes following DHA treatment were examined and the changes in the expression of MCL-1 mRNAs and MCL-1 proteins following DHA treatment were also examined. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 5 | The rate of apoptosis and cell cycle changes following DHA treatment were examined and the changes in the expression of MCL-1 mRNAs and MCL-1 proteins following DHA treatment were also examined. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 6 | Western blot analysis demonstrated that DHA treatment significantly upregulated the expression of the pro-apoptotic MCL-1S protein. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 7 | DHA affected the expression of the apoptosis-associated protein MCL-1 through multiple mechanisms. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 8 | DHA treatment increased the ratio of MCL-1S/MCL-1L protein, thus inducing apoptosis in cholangiocarcinoma cells. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 9 | DHA treatment increased the ratio of MCL-1S/MCL-1L protein, thus inducing apoptosis in cholangiocarcinoma cells. | artenimol | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |