Pub. Date : 2016 Apr
PMID : 26786889
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Nicotine inhibition of TSLP production was abolished by pretreatments with alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) antagonists, AMP-activated protein kinase (AMPK) inhibitor, and phosphoinositide 3-kinase (PI3K) inhibitors. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
2 | Nicotine inhibition of TSLP production was abolished by pretreatments with alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) antagonists, AMP-activated protein kinase (AMPK) inhibitor, and phosphoinositide 3-kinase (PI3K) inhibitors. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
3 | These results suggest that nicotine inhibits the expression of TSLP by suppressing the activation of NF-kappaB through the alpha7 nAChR-PI3K-AMPK signaling pathway. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |