Title : Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.

Pub. Date : 2016 Jan 18

PMID : 26783301






1 Functional Relationships(s)
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1 In mammalian cells, inactivation of WDR91 and WDR81, the homologs of SORF-1 and SORF-2, induces Beclin1-dependent enlargement of PtdIns3P-enriched endosomes and defective degradation of epidermal growth factor receptor. phosphatidylinositol 3-phosphate epidermal growth factor receptor Homo sapiens