Title : MEK activity controls IL-8 expression in tamoxifen-resistant MCF-7 breast cancer cells.

Pub. Date : 2016 Apr

PMID : 26780941






1 Functional Relationships(s)
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1 Taken together, our results demonstrate that IL-8 expression is regulated through a MEK/ERK-dependent pathway in TamR cells, suggesting that IL-8 and its receptors may be promising therapeutic targets for overcoming tamoxifen resistance. Tamoxifen mitogen-activated protein kinase 1 Homo sapiens