Pub. Date : 2016 Jan 18
PMID : 26779719
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We uncover compelling evidence for the cellular compartmentalization of key chemical transmission pathways, including the functional segregation of endocannabinoid (eCB) biosynthetic enzymes diacylglycerol lipase-alpha (DAGLalpha) and -beta (DAGLbeta) to neurons and microglia, respectively. | Endocannabinoids | diacylglycerol lipase, beta | Mus musculus |
| 2 | We uncover compelling evidence for the cellular compartmentalization of key chemical transmission pathways, including the functional segregation of endocannabinoid (eCB) biosynthetic enzymes diacylglycerol lipase-alpha (DAGLalpha) and -beta (DAGLbeta) to neurons and microglia, respectively. | Endocannabinoids | diacylglycerol lipase, beta | Mus musculus |
| 3 | Disruption of DAGLbeta perturbed eCB-eicosanoid crosstalk specifically in microglia and suppressed neuroinflammatory events in vivo independently of broader effects on eCB content. | Endocannabinoids | diacylglycerol lipase, beta | Mus musculus |