PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26779719-4 2016 We uncover compelling evidence for the cellular compartmentalization of key chemical transmission pathways, including the functional segregation of endocannabinoid (eCB) biosynthetic enzymes diacylglycerol lipase-alpha (DAGLalpha) and -beta (DAGLbeta) to neurons and microglia, respectively. Endocannabinoids 148-163 diacylglycerol lipase, beta Mus musculus 242-250 26779719-4 2016 We uncover compelling evidence for the cellular compartmentalization of key chemical transmission pathways, including the functional segregation of endocannabinoid (eCB) biosynthetic enzymes diacylglycerol lipase-alpha (DAGLalpha) and -beta (DAGLbeta) to neurons and microglia, respectively. Endocannabinoids 165-168 diacylglycerol lipase, beta Mus musculus 242-250 26779719-5 2016 Disruption of DAGLbeta perturbed eCB-eicosanoid crosstalk specifically in microglia and suppressed neuroinflammatory events in vivo independently of broader effects on eCB content. Endocannabinoids 33-36 diacylglycerol lipase, beta Mus musculus 14-22