Title : Oxidative stress contributes to the enhanced expression of Gqα/PLCβ1 proteins and hypertrophy of VSMC from SHR: role of growth factor receptor transactivation.

Pub. Date : 2016 Mar 1

PMID : 26747500






2 Functional Relationships(s)
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1 Furthermore, the levels of IGF-1R and EGFR proteins and not of PDGFR were also enhanced in VSMCs from SHRs, which were attenuated significantly by NAC, DPI, and PP2. pp2 epidermal growth factor receptor Rattus norvegicus
2 In addition, NAC, DPI, and PP2 also attenuated the enhanced phosphorylation of IGF-1R, PDGFR, EGFR, c-Src, and EKR1/2 in VSMCs from SHRs. pp2 epidermal growth factor receptor Rattus norvegicus