Title : Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes.

Pub. Date : 2016 Jan 8

PMID : 26746999






2 Functional Relationships(s)
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1 Consistently, testosterone enhanced the phosphorylation of AKT and nitric oxide synthase 3. Testosterone nitric oxide synthase 3 Homo sapiens
2 CONCLUSIONS: Testosterone protects cardiomyocytes against senescence caused by doxorubicin at least in part by modulating telomere binding factor 2 via a pathway involving the androgen receptor, phosphatidylinositol 3 kinase, AKT, and nitric oxide synthase 3. Testosterone nitric oxide synthase 3 Homo sapiens