Title : Noradrenaline increases intracellular glutathione in human astrocytoma U-251 MG cells by inducing glutamate-cysteine ligase protein via β3-adrenoceptor stimulation.

Pub. Date : 2016 Feb 5

PMID : 26724392






1 Functional Relationships(s)
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1 This increase was inhibited by a non-selective beta-adrenoceptor antagonist propranolol and by a selective beta3-adrenoceptor antagonist SR59230A, but not by a non-selective alpha-adrenoceptor antagonist phenoxybenzamine, or by a selective beta1-adrenoceptor antagonist atenolol or by a selective beta2-adrenoceptor antagonist butoxamine. 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate adrenoceptor beta 2 Homo sapiens