Title : The role of PON1 and CYP2D6 genes in susceptibility to organophosphorus chronic intoxication in Egyptian patients.

Pub. Date : 2016 Mar

PMID : 26723569






2 Functional Relationships(s)
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1 OBJECTIVE: to investigate a possible association between genetic polymorphisms of PON1 Q192R, and CYP2D6 G1934A as well as PON1 and pseudo-cholinesterase (PChE) enzyme activity levels and chronic organophosphate exposed patients, and hence, susceptibility for organophosphorus chronic poisoning. Organophosphates paraoxonase 1 Homo sapiens
2 CONCLUSION: PON1 192RR genotype and CYP2D6 1934A allele were found to be related to the susceptibility to organophosphate chronic toxicity in Egyptians. Organophosphates paraoxonase 1 Homo sapiens