Pub. Date : 2016 Apr
PMID : 26708294
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we showed that lipophilic digitoxin, digoxigenin, strophanthidin and proscillaridin A are P-gp substrates in cellular accumulation assays, whereas the less lipophilic convallatoxin was not. | Digitoxin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | In conclusion, we identified digitoxin, digoxigenin, strophanthidin and proscillaridin A as P-gp substrates using cellular accumulation assays and recognized lipophilicity as an important factor in selecting a suitable transport assay. | Digitoxin | ATP binding cassette subfamily B member 1 | Homo sapiens |