Title : The importance of MDR1 gene polymorphisms for tacrolimus dosage.

Pub. Date : 2016 Feb 15

PMID : 26705892






3 Functional Relationships(s)
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1 The importance of MDR1 gene polymorphisms for tacrolimus dosage. Tacrolimus ATP binding cassette subfamily B member 1 Homo sapiens
2 Polymorphisms of the multi drug resistance (MDR1) gene cause variability in P-glycoprotein mediated metabolism of tacrolimus. Tacrolimus ATP binding cassette subfamily B member 1 Homo sapiens
3 The aim of this study was to examine the relationship between MDR1 gene single nucleotide polymorphisms (SNPs) and their haplotypes with dosage of tacrolimus in kidney transplant recipients who were cytochrome (CYP) 3A5*3 homozygotes. Tacrolimus ATP binding cassette subfamily B member 1 Homo sapiens