Title : Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer.

Pub. Date : 2016 Jan

PMID : 26693899






1 Functional Relationships(s)
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1 Nevertheless, all primary platinum-sensitive HGSOCs remained HR-deficient, irrespective of whether they became resistant to second-line platinum, further suggesting these tumours qualify for second-line Poly APD ribose polymerase (PARP) inhibitor treatment. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens