Title : A selective peroxisome proliferator-activated receptor δ agonist PYPEP suppresses atherosclerosis in association with improvement of the serum lipoprotein profiles in human apolipoprotein B100 and cholesteryl ester transfer protein double transgenic mice.

Pub. Date : 2016 Jan

PMID : 26683793

1 Functional Relationships(s)
Compound Name
Protein Name
1 CONCLUSION: A novel PPARdelta agonist, PYPEP, suppressed atherosclerotic lesion progression by improving the serum lipoprotein profiles, including increased levels of ApoA-I and functional HDL particles, as well as a reduced non-HDL cholesterol level, in hApoB100/hCETP-dTg mice with human-like hypercholesterolemic dyslipidemia. Cholesterol peroxisome proliferator activator receptor delta Mus musculus