Title : [Research of the influence and mechanism about metformin on the proliferation of differentiated endometrial carcinoma cells].

Pub. Date : 2015 Sep

PMID : 26675396






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Metformin could enhance the EGFR signaling pathway inhibitor AG1478 inhibition of endometrial cancer cells, which may inhibit EGFR expression of phosphorylated proteins to inhibit the phosphorylation of ERK1/2 proteins and then inhibit proliferation of endometrial cancer cells. Metformin epidermal growth factor receptor Homo sapiens
2 Metformin could enhance the EGFR signaling pathway inhibitor AG1478 inhibition of endometrial cancer cells, which may inhibit EGFR expression of phosphorylated proteins to inhibit the phosphorylation of ERK1/2 proteins and then inhibit proliferation of endometrial cancer cells. Metformin epidermal growth factor receptor Homo sapiens