Pub. Date : 2016
PMID : 26655728
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nitric oxide (NO) generated by vascular endothelial NO synthase (eNOS) plays a critical role in the NO/ cyclic guanosine 5"-monophosphate (cGMP)-mediated pulmonary vascular function. | Cyclic GMP | nitric oxide synthase 3 | Homo sapiens |
| 2 | Here we examined whether internalization of a fifteen amino acid (KRFNSISCSSWRRKR) synthetic peptide (P3) enhances the catalytic activity of eNOS via caveolae/eNOS dissociation leading to NO release and increased cGMP production in pulmonary artery endothelial cells (EC). | Cyclic GMP | nitric oxide synthase 3 | Homo sapiens |