Title : Methotrexate pharmacokinetic genetic variants are associated with outcome in rheumatoid arthritis patients.

Pub. Date : 2016

PMID : 26652611






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The FPGS rs10106 variant was also associated with MTX survival (p = 0.005) and toxicity (p = 0.021). Methotrexate folylpolyglutamate synthase Homo sapiens
2 CONCLUSION: FPGS and ABCB1 genetic variants can influence the outcome in RA patients receiving MTX monotherapy. Methotrexate folylpolyglutamate synthase Homo sapiens