Title : Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways.

Pub. Date : 2016 Mar

PMID : 26640965






1 Functional Relationships(s)
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1 Our study shows that tianeptine attenuated the LPS-evoked inflammatory activation of microglia by decreasing the expression of proinflammatory cytokines such as IL-1beta, IL-18, IL-6 and tumor necrosis factor alpha (TNF-alpha), the release of nitric oxide (NO) and reactive oxygen species (ROS) as well as the expression of inducible nitric oxide synthase. tianeptine interleukin 6 Homo sapiens