Title : Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax.

Pub. Date : 2016 Jul 28

PMID : 26640142






1 Functional Relationships(s)
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1 We and others have demonstrated that glucose maintains levels of key resistance-promoting BCL-2 family member, myeloid cell leukemic factor 1 (MCL-1). Glucose BCL2 apoptosis regulator Homo sapiens