Title : Dewetting of S1-Pocket via Water Channel upon Thrombin-Substrate Association Reaction.

Pub. Date : 2015 Dec 31

PMID : 26634958






1 Functional Relationships(s)
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Protein Name
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1 During the MD simulation, ArgP1 in a substrate accessed thrombin"s substrate-binding pocket and formed specific hydrogen bonds (H-bonds) with Asp189 in thrombin, while the catalytic serine of thrombin was still away from the substrate"s active site. Serine diacylglycerol O-acyltransferase 1 Homo sapiens