Title : Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases.

Pub. Date : 2015 Dec 15

PMID : 26631750






2 Functional Relationships(s)
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1 The aromatase/cyclases (ARO/CYCs) are responsible for regiospecific cyclization of bacterial polyketides. Polyketides cytochrome P450 family 19 subfamily A member 1 Homo sapiens
2 This work completes the structural and functional characterization of mono- and di-domain ARO/CYCs in bacterial type II polyketide synthases and lays the groundwork for engineered biosynthesis of new bioactive polyketides. Polyketides cytochrome P450 family 19 subfamily A member 1 Homo sapiens