Title : Cooperative effect of BI-69A11 and celecoxib enhances radiosensitization by modulating DNA damage repair in colon carcinoma.

Pub. Date : 2016 May

PMID : 26631035






1 Functional Relationships(s)
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1 Here, we suggest that the combination of BI-69A11 and celecoxib inhibits the phosphorylation of ataxia telangiectasia mutated (ATM) kinase and DNA-PK responsible for ionizing radiation (IR)-induced double-strand break (DSB) repair. Celecoxib protein kinase, DNA-activated, catalytic subunit Homo sapiens