Pub. Date : 2016 Feb 5
PMID : 26627823
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Analysis of the Effects of the Bruton"s tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcgamma Receptor (FcgammaR) Function. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |
| 2 | Analysis of the Effects of the Bruton"s tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcgamma Receptor (FcgammaR) Function. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |
| 3 | The irreversible Bruton"s tyrosine kinase (Btk) inhibitor ibrutinib has shown efficacy against B-cell tumors such as chronic lymphocytic leukemia and B-cell non-Hodgkin lymphoma. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |
| 4 | The irreversible Bruton"s tyrosine kinase (Btk) inhibitor ibrutinib has shown efficacy against B-cell tumors such as chronic lymphocytic leukemia and B-cell non-Hodgkin lymphoma. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |
| 5 | Pretreatment of monocytes with IFNgamma abrogated the effects of ibrutinib on FcgammaR-mediated cytokine production, suggesting that IFNgamma priming could overcome this Btk inhibition. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |