Title : Shifting the feeding of mice to the rest phase creates metabolic alterations, which, on their own, shift the peripheral circadian clocks by 12 hours.

Pub. Date : 2015 Dec 1

PMID : 26627259






2 Functional Relationships(s)
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1 In turn, peroxisome proliferator-activated receptor alpha (PPARalpha) activation by free fatty acid (FFA), and cAMP response element-binding protein (CREB) activation by glucagon, lead to further metabolic alterations during the circadian active phase, as well as to aberrant activation of expression of the PCC components nuclear receptor subfamily 1, group D, member 1 (Nr1d1/RevErbalpha), Period (Per1 and Per2). Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus
2 In turn, peroxisome proliferator-activated receptor alpha (PPARalpha) activation by free fatty acid (FFA), and cAMP response element-binding protein (CREB) activation by glucagon, lead to further metabolic alterations during the circadian active phase, as well as to aberrant activation of expression of the PCC components nuclear receptor subfamily 1, group D, member 1 (Nr1d1/RevErbalpha), Period (Per1 and Per2). Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus