Title : Modulation of mitochondrial dysfunction in neurodegenerative diseases via activation of nuclear factor erythroid-2-related factor 2 by food-derived compounds.

Pub. Date : 2016 Jan

PMID : 26626189






1 Functional Relationships(s)
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1 Small food-derived inducers of the Nrf2/ARE pathway including l-sulforaphane from broccoli and isoliquiritigenin from licorice displayed promising protection of mitochondrial function in models of oxidative stress and neurodegenerative diseases and represent a novel approach to prevent and treat aging-associated neurodegenerative diseases. isoliquiritigenin NFE2 like bZIP transcription factor 2 Homo sapiens