Pub. Date : 2016 Jan 5
PMID : 26607348
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Puerarin protects mouse liver against nickel-induced oxidative stress and inflammation associated with the TLR4/p38/CREB pathway. | puerarin | toll-like receptor 4 | Mus musculus |
| 2 | Puerarin significantly inhibited the TLR4 activation and p38 MAPK phosphorylation, which in turn inhibited NF-kappaB activity. | puerarin | toll-like receptor 4 | Mus musculus |
| 3 | Data from this study suggested that the inhibition of Ni-induced oxidative stress and inflammatory responses by puerarin is due to its ability to modulate the TLR4/p38/CREB signaling pathway. | puerarin | toll-like receptor 4 | Mus musculus |