Title : Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.

Pub. Date : 2016 Jan 12

PMID : 26593251






1 Functional Relationships(s)
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1 We also showed that inhibition of PDK1 with DAP increased the cleavage of pro-apoptotic proteins (PARP and Caspase 3) and decreased the expression of the anti-apoptotic proteins (BCL-xL and BCL-2) and autophagy regulators (ULK1, Beclin-1 and Atg). 2,2-dichloroacetophenone BCL2-like 1 Mus musculus