Title : Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma.

Pub. Date : 2015

PMID : 26586952






2 Functional Relationships(s)
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1 On the other hand, although the second-generation mTOR inhibitor, PP242, has exerted substantial efficacy, it was revealed that independent inhibition by PP242 was transient, which could lead to positive-feedback loop to EGFR. PP242 mechanistic target of rapamycin kinase Homo sapiens
2 On the other hand, although the second-generation mTOR inhibitor, PP242, has exerted substantial efficacy, it was revealed that independent inhibition by PP242 was transient, which could lead to positive-feedback loop to EGFR. PP242 mechanistic target of rapamycin kinase Homo sapiens