Title : ETME, a novel β-elemene derivative, synergizes with arsenic trioxide in inducing apoptosis and cell cycle arrest in hepatocarcinoma cells via a p53-dependent pathway.

Pub. Date : 2014 Dec

PMID : 26579413






1 Functional Relationships(s)
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1 The combination also decreased the MMP, down-regulated Bcl-2 and pro-proteins of the caspase family, and up-regulated Bax and BID, all of which were reversed by the p53 inhibitor, pifithrin-alpha. pifithrin BH3 interacting domain death agonist Homo sapiens