Pub. Date : 2016 Mar
PMID : 26578688
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The beta2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion. | Cyclic AMP | adrenoceptor beta 2 | Homo sapiens |
| 2 | beta2AR activation results in elevated cAMP (formoterol pEC50 9.86 +- 0.32), increased intracellular Ca(2+) (formoterol pEC50 8.20 +- 0.33) and reduced phosphorylated ERK (pERK; formoterol pIC50 11.62 +- 0.31). | Cyclic AMP | adrenoceptor beta 2 | Homo sapiens |