Title : SIRT1-dependent myoprotective effects of resveratrol on muscle injury induced by compression.

Pub. Date : 2015

PMID : 26557094






1 Functional Relationships(s)
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1 In parallel, resveratrol augmented the expression level and activity of SIRT1 and phosphorylation levels of Foxo3a and Akt while suppressed the increases in protein abundances of p53, Bax, MAFbx, and ubiquitin, enzymatic activities of caspase 3 and 20S proteasome, and apoptotic DNA fragmentation in the compressed muscle. Resveratrol BCL2 associated X, apoptosis regulator Rattus norvegicus