Pub. Date : 2015 Jul
PMID : 26540910
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [The study of siRNA interference after laryngeal cancer Hep-2 cells to cisplatin sensitivity of beta-catenin gene expression]. | Cisplatin | catenin beta 1 | Homo sapiens |
| 2 | OBJECTIVE: To investigate the changes of laryngeal cancer Hep-2 cells to cisplatin chemosensitivity after the interference of siRNA of beta-catenin gene expression. | Cisplatin | catenin beta 1 | Homo sapiens |
| 3 | The IC50 calculation software showed that IC50 of cisplatin on beta-catenin-siRNA IC50 interference group is (5.81 +- 0.46)mug/ml, the blank control group is (10.10 +- 1.01) mug/ml, the difference between the two groups has statistical signifi- cance (P < 0.01). | Cisplatin | catenin beta 1 | Homo sapiens |
| 4 | CONCLUSION: To interfere the expression of beta-catenin can effectively enhance the sensitivity of laryngeal cancer cells to chemotherapeutic drugs cisplatin. | Cisplatin | catenin beta 1 | Homo sapiens |