Title : The Inhibitory Effect of Ciprofloxacin on the β-Glucuronidase-mediated Deconjugation of the Irinotecan Metabolite SN-38-G.

Pub. Date : 2016 May

PMID : 26518357






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Ciprofloxacin and phenolphthalein-beta-D-glucuronide (PhePG), a typical beta-glucuronidase substrate, significantly decreased SN-38-G deconjugation and, hence SN-38 formation. phenolphthalein glucuronide glucuronidase beta Homo sapiens
2 Ciprofloxacin and phenolphthalein-beta-D-glucuronide (PhePG), a typical beta-glucuronidase substrate, significantly decreased SN-38-G deconjugation and, hence SN-38 formation. phenolphthalein glucuronide glucuronidase beta Homo sapiens