Title : A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.

Pub. Date : 2015 Dec 1

PMID : 26517687






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 STF-083010, a novel inhibitor which specifically blocks the XBP1 splicing, reestablishes tamoxifen sensitivity to resistant MCF-7 cells. STF 083010 X-box binding protein 1 Homo sapiens