Title : Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma.

Pub. Date : 2016 Jan 5

PMID : 26517522






1 Functional Relationships(s)
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1 Quantitative real time PCR, fluorescent microscopy, and cell migration assays all confirmed that Lovastatin inhibits integrin alphavbeta3 downstream signaling including FAK activation, and beta-catenin, vimentin, ZO-1, and beta-actin. Lovastatin vimentin Homo sapiens