Title : Influence of sesamin on CYP2C-mediated diclofenac metabolism: in vitro and in vivo analysis.

Pub. Date : 2015 Oct

PMID : 26516586






2 Functional Relationships(s)
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1 Influence of sesamin on CYP2C-mediated diclofenac metabolism: in vitro and in vivo analysis. Diclofenac cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
2 The pharmacokinetics of diclofenac, which is mainly metabolized by CYP2C11 in male rats, were investigated after a 3-days administration of sesamin (0, 10, and 100 mg/kg bw). Diclofenac cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus