Pub. Date : 2015 Nov 17
PMID : 26515463
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The diverse range of substrates of ABCG2 includes many antineoplastic agents such as topotecan, doxorubicin and mitoxantrone. | Topotecan | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |
| 2 | In a murine model system, combination treatment of A-803467 (35 mg/kg) and topotecan (3 mg/kg) significantly inhibited the tumor growth in mice xenografted with ABCG2-overexpressing cancer cells. | Topotecan | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |