Title : Esophageal cancer and microelements.

Pub. Date : 1989 Apr

PMID : 2651504






1 Functional Relationships(s)
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1 We have demonstrated that dietary zinc deficiency increased the cytochrome P-450-dependent microsomal metabolism of methylbenzylnitrosamine and dimethylnitrosamine, two members of this class of dialkylnitrosamine carcinogens, while the addition of zinc in vitro noncompetitively inhibits the microsomal metabolism of these carcinogens. Dimethylnitrosamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens