Title : O-Linked N-acetylglucosaminylation of Sp1 interferes with Sp1 activation of glycolytic genes.

Pub. Date : 2015 Dec 4-11

PMID : 26499076






1 Functional Relationships(s)
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1 Glycolysis, the primary pathway metabolizing glucose for energy production, is connected to the hexosamine biosynthetic pathway (HBP) which produces UDP-N-acetylglucosamine (UDP-GlcNAc), a GlcNAc donor for O-linked GlcNAc modification (O-GlcNAc), as well as for traditional elongated glycosylation. Hexosamines O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens