Title : The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype.

Pub. Date : 2015 Oct 24

PMID : 26498662






1 Functional Relationships(s)
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1 CONCLUSION: Estrogen pretreatment of breast cancer cells increases PR steady state levels, resulting in an unequivocal progesterone response that upregulates key members of growth factor pathways. Progesterone progesterone receptor Homo sapiens