Title : Insulin Fibrillization at Acidic and Physiological pH Values is Controlled by Different Molecular Mechanisms.

Pub. Date : 2015 Dec

PMID : 26493286






1 Functional Relationships(s)
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1 The latter effect indicates that protonation of histidine residues seems to be important for the fibrillization of monomeric insulin, whereas the pH effect at high concentration may result from off-pathway oligomerization propensity. Histidine insulin Homo sapiens